The more I watch the later epsiodes of Big Bang Theory - which I find rather sweet, despite understanding why it winds up so many geeks/academics - the more clear it becomes that the only real difference between a lot of US comedy and US drama is that in the latter you're actually aloud to punch someone who's being an intolerable douche, rather than have to play along for the sake of setting up jokes.
How about it, Chuck Lorre? Dip into the drama pool a little. Consider the conflict-resolution advantages offered by a good sock to the jaw. If there is any character in modern sitcoms who needs a fist in the face more than Sheldon Cooper, they have managed to avoid showing up on my radar.